Operation: Rebirth, also called Project: Rebirth, is an US government project originally administered by the US Army to create a new line of Supersoldiers for its World War II effort. It was part of a larger operation known as Weapon Plus. It was headed up by Dr. Abraham Erskine.
Abraham Erskine was the scientist who first developed the Super-Soldier Serum, as well as the Vita-Rays designed to create an army of enhanced human beings whose physical defects and limitations would be eliminated for the USA World War II efforts.
His first efforts with the serum were deemed as failures. However, Erskine continued to refine the process. After weeks of tests, Steve Rogers was at last administered the Super-Soldier Serum. Given part of the compound intravenously and another part orally, Rogers was then bombarded by vita-rays, a special combination of exotic wavelengths of radiation designed to accelerate and stabilize the serum’s effect on his body. Steve Rogers emerged from the vita-ray chamber with a perfect human body. A Nazi spy, who observed the experiment, murdered Dr. Erskine mere minutes after its conclusion. Dr. Erskine died without fully committing the Super-Soldier formula to paper, leaving Rogers the sole beneficiary of his genius.
With Erskine’s murder, Wilfred Nagel took over the American program. His attempt to recreate Erskine’s successful process did not succeed in mass production. Nagel’s early attempts to recreate Erskine’s successful chemical formula resulted in African-American super soldiers, most prominently Isaiah Bradley. Three hundred African-American soldiers were taken from Camp Cathcart and subjected to potentially fatal experiments at an undisclosed location in an attempt to recreate Erskine’s Rogers successful Super-Soldier Formula version. Only five men survived the original trials; hundreds of test subjects left behind at Camp Cathcart and the camp’s commander were executed by US soldiers in the name of secrecy, the families of the three hundred were told that they had died in battle.
Although there were many later attempts to recreate or reverse-engineer Operation: Rebirth’s Super-Soldier Serum in detail, none are known to have been involved with Weapon Plus except for the attempt that resulted in the creation of Isaiah Bradley’s son Josiah X nor have been successful in replicating the missing Vita Ray part as with Steve Rogerswho was to have accurately recreated the chemical part of the successful sample. Weapon Plus considers Steven Rogers as its most successful creation.
A second Project Rebirth was endorsed by the US Military, using the tamed alien symbiote Venom with veteran Flash Thompson in order to create a new Super-Solider: Agent Venom. Flash became the new Venom when he was enlisted as a part of Project Rebirth. Flash was bonded with the symbiote, recently acquired by the U.S. government after Mac Gargan’s arrest after the Siege of Asgard. While bonded, Flash was able to reproduce his legs and had powers comparable to Spider-Man.